Report
Assessment Effects On Alcohol Use By Persons With HIV In Rural Uganda

Author
Nneka I. Emenyonu (E-mail: Nneka.Emenyonu@ucsf.edu), Robin Fatch, Winnie R. Muyindike, Allen Kekibiina, Sarah Woolf-King, and Judith A. Hahn
Citation
Randomized Study of Assessment Effects on Alcohol Use by Persons With HIV in Rural Uganda Nneka I. Emenyonu, Robin Fatch, Winnie R. Muyindike, Allen Kekibiina, Sarah Woolf-King, and Judith A. Hahn Journal of Studies on Alcohol and Drugs 2017 78:2, 296-305
  • Source
    Journal of Studies on Alcohol and Drugs
  • Release date
    21/03/2017

Randomized Study of Assessment Effects on Alcohol Use by Persons With HIV in Rural Uganda

Objective

Alcohol use is a crucial driver of HIV in sub-Saharan Africa, and interventions are needed. The goal of this study was to assess whether assessment itself (assessment reactivity) causes declines in alcohol use in a research study in persons with HIV in Uganda.

Method

Study participants were adult patients of the Immune Suppression Syndrome (ISS) Clinic in Mbarara, Uganda, who were new to HIV care and reported any alcohol consumption in the prior year. Participants were randomized to (a) a study cohort, with structured interviews, breath alcohol analysis tests, and blood draws conducted quarterly, or (b) a minimally assessed arm that engaged in these procedures only once, at 6 months after baseline.

The main outcome was alcohol use at 6 months, defined as Alcohol Use Disorders Identification Test-Consumption [AUDIT-C] positive (≥3 for women, ≥4 for men) or phosphatidylethanol (PEth; an alcohol biomarker) level ≥ 50 ng/ml.

The researchers also examined this outcome stratified by gender.

Results

The researchers examined 175 and 139 persons in the quarterly assessed versus minimally assessed arms, respectively. Overall, 54.8% were male, the median age was 30 (interquartile range: 25–36), and 58.0% initiated anti-retroviral therapy at 6 months. Nearly equal proportions (53.7% and 51.1% in the study quarterly assessed vs. minimally assessed arm, respectively) engaged in alcohol use in the 3 months before the 6-month study visit (p = .64), and the researchers found no evidence of interaction by gender (p = .36).

Conclusions

The researchers found no evidence of assessment reactivity in a study that included quarterly study visits. Assessment is not sufficient to act as an intervention itself in this population with high levels alcohol consumption. Interventions are needed to decrease alcohol consumption in this population.

Source Website: Journal of Studies on Alcohol and Drugs